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General Catalyst has in recent years increased its focus on artificial intelligence and other cutting-edge technologies. Their investments include names like Anthropic (artificial intelligence), Stripe (financial technology), Anduril (defense technology), and Airbnb. They're also into crypto and blockchain projects.
Lately, they've expanded by acquiring La Famiglia, Ohio's Summa Health, and merging with India's Venture Highway.

Assets under management grew to more than $40 billion by summer 2025.