Kofi Ampadu, the partner at a16z who led the firm’s Talent x Opportunity (TxO) fund and program, has left the firm, according to an email he sent to staff that Read obtained. This comes months after the firm paused TxO and laid off most of its staff.

“During my time at the firm, I was deeply grateful for the opportunity and the trust to lead this work,” Ampadu wrote in the email, sent Friday afternoon, with the subject line “Closing My a16z Chapter.”

“Identifying out-of-network entrepreneurs and supporting them as they sharpened their ideas, raised capital, and grew into confident leaders was one of the most meaningful experiences of my career,” he wrote.

Ampadu led the program, which launched in 2020, for over four years until its pause last November, taking over for the initial leader, Nait Jones. Afterward, Ampadu seems to have worked at a16z’s latest accelerator, Speedrun.

Ampadu’s departure perhaps signals the end of the TxO chapter. The fund and program focused on supporting underserved founders by providing access to tech networks and investment capital through a donor-advised fund. Though some founders spoke highly of the program, others criticized the controversial donor-advised structure. The program also launched a grant program in 2024 to provide $50,000 to nonprofits that help diverse founders.

Its last cohort was in March 2025, and its indefinite pause came as many top tech names reframe, cut, or eliminate prior public commitments to diversity, equity, and inclusion. We’ve reached out to a16z and Ampadu for comment.

His full note below: