Tooth Regeneration Human Trial: Bones in the human body can heal themselves if broken, but once teeth fall out, they do not grow back naturally. This is why millions of people around the world have to rely on artificial teeth or implants. But now this situation is going to change. from Japan Scientists have discovered such a drug, which makes the human mouth natural again teeth can grow
Dr. Head of Dental Research at Kitano Hospital in Osaka. Human trials of the drug have begun since September 2024, led by Katsu Takahashi. The 11-month trial involved 30 men aged 30 to 64 with at least one missing tooth. The drug is given as an ‘intramuscular’ (through the muscle) injection and is being tested for safety and efficacy.
This research USAG-1 The name is based on a specific protein. In the human body, this protein works to prevent the growth of teeth. Kyoto University scientists have developed a ‘monoclonal antibody’ that blocks USAG-1. When this protein is inactive, bone growth factor (BMP) is activated and helps new teeth grow. In animal tests, this drug has been shown to stimulate new tooth growth.
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If this trial in men is successful, the next phase of this research will be even more important:
1. Experiments on children: Children between 2 to 7 years of age will be treated, who are not born with teeth (Congenital Anodontia).
2. General Availability: Scientists aim to make the drug available to the general public in hospitals by 2030.
Tooth loss is not only an aesthetic issue but also a major digestive and health issue. If this drug is successful, there will be no need for dentures or expensive dental implants in the future.
Not only because it is old, but also when ‘these’ things appear, it is necessary to change the toothbrush
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