People taking venlafaxine are being urged to keep an eye out for a variety of symptoms and side effects that will warrant a call to either 111 or their doctor. Venlafaxine is a commonly prescribed SNRI (serotonin and noradrenaline reuptake inhibitor) that is mainly prescribed to treat depression, although it can sometimes be used to treat anxiety and panic attacks.

It is generally prescribed as either a tablet or capsule to be swallowed and works by increasing the levels of serotonin and noradrenaline in the brain, which can help enhance a person's mood. While guidance from the NHS notes that venlafaxine has fewer side effects than older antidepressants, this doesn't mean there aren't any side effects.

Typically, it takes four to six weeks for venlafaxine to fully work, although people taking it tend to feel better after one to two weeks. While common side effects of venlafaxine include sweating, feeling sick, dry mouth, and headaches, the NHS notes that these are usually mild and go away after a couple of weeks.

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Despite this, some other side effects may be considered more serious and could require a call to 111 or a doctor. Such serious side effects are uncommon and affect less than one in 100 people taking venlafaxine.

Guidance from the NHS highlights that you should book an appointment with your doctor if you gain or lose weight without trying or experience significant changes to your periods - this can include bleeding between periods, heavy bleeding, or spotting. Otherwise, patients are urged to call their doctor or 111 if they experience the following side effects:

• The whites of your eyes or skin turn yellow


• Bleeding from the gums


• Bruises that appear without a reason or that get bigger


• You have thoughts about harming yourself or ending your life


• Unexplained muscle pain or weakness


• Shortness of breath, or a fast or irregular heartbeat


• You experience feelings of overwhelming happiness (euphoria), excessive enthusiasm or excitement, or a feeling of restlessness that means you cannot sit or stand still


• Any changes in eyesight, such as blurred vision or dilated pupils


• You cough up blood


• Have blood in your pee


• You get constant headaches, long-lasting confusion, weakness, or frequent muscle cramps


• You have black or red poo, or blood in your vomit – these can be signs of bleeding in the stomach

Keep in mind that the NHS notes taking venlafaxine over a long period is generally safe and there are no lasting effects. However, if you are concerned bout any side effects relating to your medication, you should either speak to a qualified pharmacist, doctor, or relevant health professional.

Further guidance on venlafaxine can be found on the NHS website here.